diff --git a/Lib/csv.py b/Lib/csv.py
index 6cae34c705777d..96845831f17e5e 100644
--- a/Lib/csv.py
+++ b/Lib/csv.py
@@ -280,12 +280,16 @@ def _guess_quote_and_delimiter(self, data, delimiters):
         """
         import re
 
+        # The body of a quoted field ends at the first quote which is
+        # not doubled, as it does for a reader.  A lazy ".*?" scans to
+        # the end of the sample instead, from every start: quadratically.
+        body = r'(?:(?P=quote){2}|(?!(?P=quote)).)*+'
         matches = []
-        for restr in (r'(?P<delim>[^\w\n"\'])(?P<space> ?)(?P<quote>["\']).*?(?P=quote)(?P=delim)',   # ,".*?",
-                      r'(?:^|\n)(?P<quote>["\']).*?(?P=quote)(?P<delim>[^\w\n"\'])(?P<space> ?)',     #  ".*?",
-                      r'(?P<delim>[^\w\n"\'])(?P<space> ?)(?P<quote>["\']).*?(?P=quote)(?:$|\r|\n)',  # ,".*?"
-                      r'(?:^|\n)(?P<quote>["\']).*?(?P=quote)(?:$|\r|\n)'):                           #  ".*?" (no delim, no space)
-            regexp = re.compile(restr, re.DOTALL | re.MULTILINE)
+        for restr in (r'(?P<delim>[^\w\n"\'])(?P<space> ?)(?P<quote>["\'])%s(?P=quote)(?P=delim)',   # ,"...",
+                      r'(?:^|\n)(?P<quote>["\'])%s(?P=quote)(?P<delim>[^\w\n"\'])(?P<space> ?)',     #  "...",
+                      r'(?P<delim>[^\w\n"\'])(?P<space> ?)(?P<quote>["\'])%s(?P=quote)(?:$|\r|\n)',  # ,"..."
+                      r'(?:^|\n)(?P<quote>["\'])%s(?P=quote)(?:$|\r|\n)'):                           #  "..." (no delim, no space)
+            regexp = re.compile(restr % body, re.DOTALL | re.MULTILINE)
             matches = regexp.findall(data)
             if matches:
                 break
diff --git a/Lib/test/test_csv.py b/Lib/test/test_csv.py
index 2ab529b51c207d..03bcf9c9e0ea15 100644
--- a/Lib/test/test_csv.py
+++ b/Lib/test/test_csv.py
@@ -1564,6 +1564,14 @@ def test_zero_mode_tie_order_colon_first(self):
             sniffer.sniff(sample)
 
 
+    def test_sniff_quoted_single_column(self):
+        # gh-98820: this sample used to take minutes.
+        sniffer = csv.Sniffer()
+        sample = '"abcdefghijklmnopqrstuvwxyz"\n' * 10000
+        with self.assertRaisesRegex(csv.Error, "Could not determine delimiter"):
+            sniffer.sniff(sample, delimiters=',:|\t')
+
+
 class NUL:
     def write(s, *args):
         pass
diff --git a/Misc/NEWS.d/next/Library/2026-07-29-11-20-00.gh-issue-98820.Qm7Hs4.rst b/Misc/NEWS.d/next/Library/2026-07-29-11-20-00.gh-issue-98820.Qm7Hs4.rst
new file mode 100644
index 00000000000000..aa9ae8d937004f
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2026-07-29-11-20-00.gh-issue-98820.Qm7Hs4.rst
@@ -0,0 +1,2 @@
+Fix quadratic time in :meth:`csv.Sniffer.sniff` for a sample which contains
+quoted fields, in particular for a single column of quoted fields.