diff --git a/vulnerabilities/models.py b/vulnerabilities/models.py
index 826d35a54..952f3ce86 100644
--- a/vulnerabilities/models.py
+++ b/vulnerabilities/models.py
@@ -2926,7 +2926,10 @@ def to_dict(self):
 
 class AdvisoryV2QuerySet(BaseQuerySet):
     def latest_for_avid(self, avid: str):
-        return self.get(avid=avid, is_latest=True)
+        try:
+            return self.get(avid=avid, is_latest=True)
+        except self.model.DoesNotExist:
+            return None
 
     def latest_per_avid(self):
         return self.filter(is_latest=True)
diff --git a/vulnerabilities/tests/test_advisory_details_view.py b/vulnerabilities/tests/test_advisory_details_view.py
new file mode 100644
index 000000000..f7d060411
--- /dev/null
+++ b/vulnerabilities/tests/test_advisory_details_view.py
@@ -0,0 +1,44 @@
+#
+# Copyright (c) nexB Inc. and others. All rights reserved.
+# VulnerableCode is a trademark of nexB Inc.
+# SPDX-License-Identifier: Apache-2.0
+# See http://www.apache.org/licenses/LICENSE-2.0 for the license text.
+# See https://github.com/aboutcode-org/vulnerablecode for support or download.
+# See https://aboutcode.org for more information about nexB OSS projects.
+#
+
+import time
+
+import pytest
+from django.urls import reverse
+
+INVALID_AVID = "pysec/PYSEC-3000-0"
+
+
+@pytest.mark.django_db
+@pytest.mark.parametrize(
+    "url_name",
+    [
+        "advisory_details",
+        "advisory_package_details",
+        "advisory_package_commit_details",
+    ],
+)
+def test_advisory_views_return_404_for_invalid_avid(client, url_name):
+    """
+    Requesting an advisory-related page for an avid that does not exist should
+    return a 404 Page Not Found, not a 500 Server Error.
+
+    Regression test for: "Advisory Page Returns 500 Instead of 404 for Invalid
+    Advisory IDs".
+    """
+    # Satisfy AltchaProtectionMiddleware so the request reaches the view
+    # instead of being redirected to the captcha page.
+    session = client.session
+    session["altcha_verified_at"] = time.time()
+    session.save()
+
+    url = reverse(url_name, kwargs={"avid": INVALID_AVID})
+    response = client.get(url)
+
+    assert response.status_code == 404
diff --git a/vulnerabilities/tests/test_same_avid_different_content_id.py b/vulnerabilities/tests/test_same_avid_different_content_id.py
index 6e60ab4c3..750450fbd 100644
--- a/vulnerabilities/tests/test_same_avid_different_content_id.py
+++ b/vulnerabilities/tests/test_same_avid_different_content_id.py
@@ -68,6 +68,20 @@ def test_latest_for_avid_tie_breaks_by_id(advisory_factory, django_assert_num_qu
     assert result.id == second.id
 
 
+@pytest.mark.django_db
+def test_latest_for_avid_returns_none_for_unknown_avid(django_assert_num_queries):
+    """
+    ``latest_for_avid`` should return ``None`` (not raise ``DoesNotExist``) for an
+    avid that does not exist, since callers rely on a falsy return value to
+    raise an ``Http404``. See GH issue: Advisory Page Returns 500 Instead of 404
+    for Invalid Advisory IDs.
+    """
+    with django_assert_num_queries(1):
+        result = AdvisoryV2.objects.latest_for_avid("does-not-exist/ADV-404")
+
+    assert result is None
+
+
 @pytest.mark.django_db
 def test_latest_per_avid_returns_one_row_per_avid(advisory_factory, django_assert_num_queries):
     advisory_factory(advisory_id="A", summary="old advisory")